CMR myocardial tissue characterization in a mouse model of doxorubicin-induced cardiotoxicity
نویسندگان
چکیده
Background Cardiotoxicity is a major limiting factor preventing dose-effective use of multiple cytotoxic agents in cancer treatment. Current cardiotoxicity diagnosis is based on functional changes that occur late in the course of the disease. In this pre-clinical pilot study, we hypothesize myocardial T1 and T2 mapping will identify mice at risk of death secondary to doxorubicin-induced cardiotoxicity prior to cardiac function deterioration.
منابع مشابه
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عنوان ژورنال:
دوره 17 شماره
صفحات -
تاریخ انتشار 2015